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A high-performance retinol renewal serum designed to visibly smooth, refine, and rejuvenate the skin while maintaining hydration and comfort. Powered by advanced liposomal retinol technology, this formula delivers deep, targeted results to improve the appearance of fine lines, wrinkles, and uneven texture—without the typical dryness associated with retinol.
Perfect for anyone experiencing:
Suitable for most skin types, including those new to retinol, with proper introduction.
Aqua (Deionized Water), Glycerin (Kosher Vegetable), Hamamelis Virginiana Water (Witch Hazel), Organic Aloe Barbadensis Leaf Juice (Aloe Vera), Simmondsia Chinensis Seed (Organic Jojoba) Oil, Triticum Vulgare (Wheat) Germ Oil, Retinol Liposome (Water, Pentylene Glycol, Lecithin, Retinol, Polysorbate 20, Glycerin, Tocopherol, Ethanol, Potassium Phosphate, Sodium Hydroxide), Phenoxyethanol, Cassia Angustifolia Seed Polysaccharide (Plant Based Hyaluronic Acid), Tocopheryl Acetate (Vitamin E), Camellia Sinensis Leaf (Organic Green Tea) Extract, Resina Propoli (Propolis) Extract, Organic Centella Asiatica (Gotu Kola) Extract, Equisetum Arvense Extract (Horsetail) Extract, Taraxacum Officinale (Dandelion) Extract, Geranium Maculatum (Wild Geranium) Extract, Hydroxyethyl Ethylcellulose, Carrageenan Gum, Sodium Benzoate, Potassium Sorbate, Ethylhexylglycerin.
Designed as a true skin-renewal treatment, this advanced retinol serum works deep within the skin to visibly smooth texture, refine pores, and soften the look of fine lines—while maintaining the hydration and balance your skin needs.
At the heart of the formula is Centersome®RL Liposomal Retinol, an intelligent delivery system that enhances penetration while allowing for a more controlled, gentle release. This means effective skin renewal without the harshness traditionally associated with retinol.
A stabilized, liposomal form of retinol helps:
→ Smooth the appearance of fine lines and wrinkles
→ Refine uneven texture and roughness
→ Support natural cell turnover for fresher-looking skin
2 To 3 Pumps
EVENINGS
After Cleansing
ON FACE
Avoid Eye Area
Apply to cleansed skin in the evening and gently massage until absorbed. Follow with a moisturizer.




No, the Advanced Retinol 2.5% Renew Serum is formulated for individuals with prior retinol experience. If you’re new to retinol, we recommend starting with our 0.5% Encapsulated Retinol Cream to allow your skin to build tolerance. Once your skin adjusts, you can transition to the 2.5% serum for enhanced benefits.
Apply a pea-sized amount of the serum to clean, dry skin in the evening, avoiding the eye area. Follow with a moisturizer to lock in hydration. Begin by using the serum twice a week, gradually increasing frequency as your skin builds tolerance. Always apply sunscreen during the day, as retinol can increase skin sensitivity to sunlight.
It’s advisable to avoid combining retinol with other potent actives like alpha-hydroxy acids (AHAs), beta-hydroxy acids (BHAs), or vitamin C in the same routine, as this may cause irritation. If you wish to use these ingredients, consider alternating them on different nights or using them at different times of the day.
With consistent use, you may notice improvements in skin texture, reduced fine lines, and a more even complexion within 8 to 12 weeks. Individual results may vary based on skin type and adherence to the regimen.
Some users may experience mild redness, dryness, or peeling during the initial weeks of use, which is normal as the skin adjusts to retinol. To minimize these effects, start with a lower frequency of application and ensure adequate moisturization. If irritation persists, discontinue use and consult a dermatologist.
This product definitely works! I have been using it for approximately a year and a half now and after the first month I could already see an improvement in my complexion! Now, my friends are telling me I must be getting younger, not older, and want to know what I am using. I am happy to tell them I am using bioBare skincare! Thanks, bioBare!!
The texture is lightweight and absorbs quickly without any greasiness.
I’ve been using this retinol serum for a month, and my skin looks so much smoother!
Am very impressed with this Retinol 2.5% Renew Serum. Just turned 74 and it makes my skin look and feel baby soft! BioBare is definitely ahead of the crowd for me in terms of quality and results.
My skin has a fresh glow every morning since I started using this.
